MMP14 and central nervous system cancer: To identify profile of glioma-based miRNAs which regulate expression of MMP14 and are altered by TMZ/XRT treatment, we applied the miFinder SAbioscience platform to the total miRNAs isolated from U87 cells treated with TMZ/ XRT (100 μmol/L+2 Gy/daily) or DMSO for 48 h.