HOTAIR and neoplasm: As shown in Figure 6B, following the treatment with cisplatin, the average weight of tumors formed from siRNA/HOTAIR1 or siRNA/control-transfected A549/DDP cells was 204.8±6.8 mg and 423.4±8.4 mg, respectively, and thus, the downregulation of HOTAIR expression led to a 51.8% inhibition of tumor growth (P<0.01).