CEP152 and Seckel syndrome: Further insights in this area might be derived through gaining an understanding of why homozygous mutations within CPAP and CEP152 can cause both MCPH [8], in which microcephaly is an isolated anatomical feature, and in other cases, Seckel syndrome [12,58,59], in which microcephaly occurs as part of a more extensive phenotype involving characteristic facial features and severe short stature.