SLC40A1 and anemia (phenotype): As a consequence of these regulatory processes that control deployment of ferroportin in the plasma membrane, iron is absorbed more efficiently by the intestine, released from ferritin stores, and recycled rapidly by cells of internal organs in response to iron lack/anemia/hypoxia/blood loss, while the reverse occurs when iron is readily available, storage levels are high, or the body is in a state of inflammation or infection.