TNF and rheumatoid arthritis: This seems similar between the three most used anti-TNF agents infliximab, adalimumab and etanercept (no data are available on certolizumab and golimumab), although the proportion of patients in whom the drug can be safely tapered seems to depend on the design of the study and context (especially authorized or higher than authorized dosage, dose reduction or stopping, and in early or established RA).