It has been reported that miR-142-3p controls the target gene RAC1 and inhibits liver cancer cell proliferation and invasion [42], that miR-204a negatively controls the target gene Bcl-2 to promote apoptosis [43], and that miR-125b was upregulated in Taxol-resistant cells, causing a marked inhibition of Taxol-induced cytotoxicity and apoptosis and a subsequent increase in the resistance to Taxol in cancer cells [44]. This evidence concerns the gene RAC1 and cancer.