To elucidate the role of antileukotrienes and corticosteroids in the control of changes in asthma remodeling, we evaluated the effects of montelukast or dexamethasone treatments on eosinophilic recruitment, including its activation by detecting eotaxin and RANTES positive cells in airways and lung parenchyma in guinea pigs (GP), with chronic allergic lung inflammation. This evidence concerns the gene CCL11 and asthma.