CXCL8 and infection: As in the case of oral infection, the importance of IL-17 in protection against infection seems to be crucial to attain a mucosal barrier in the intestine as in case of Salmonella [30, 38], in mediating protection against oral brucellosis [39], promoting granulopoiesis through induction of granulocyte colony-stimulating factor G-CSF [40], and neutrophil influx through inducing neutrophil chemotactic CXCL8 (IL-8), macrophage chemotactic protein (MCP)-1, and macrophage inflammatory proteins- (MIP-) 1 and MIP-2 [9, 40, 41].