CCNE1 and systemic lupus erythematosus: Furthermore, we found that, Cyclin E and CDK2 were expressed more in the cytoplasm of the BM-MSCs from SLE patients, whereas lower levels were found in the nuclei of the BM-MSCs from SLE patients than that of the normal control (Figures 4(b), 4(c), 4(e) and 4(f); P < 0.05, resp).