TP53 and systemic lupus erythematosus: We found that p53 and p21 were expressed more in the nuclei of the BM-MSCs from SLE patients, whereas lower levels were found in the cytoplasm of the BM-MSCs from SLE patients than that of the normal control (Figures 3(b), 3(c), 3(e), and 3(f); P < 0.05, resp).