This has been supported by results in lung cancer, where a study evaluating Ebi3 levels in lung cancer patients found that Ebi3 levels are elevated in patients with malignancy, predicts for poor outcome, and is an independent prognostic indicator of disease (although this study only examined Ebi3, and not the p35 subunit of IL-35) (40). The gene discussed is EBI3; the disease is lung cancer.