MAPT and neuroblastoma: Interestingly, we recently found that all of the major players in the above hypothetical scenario (Wnt markers, GSK3b, tau, fyn, MARK1, autophagy markers and NMDA, AMPA, and cholinergic receptor subunits) are enriched in exosomes released by neuroblastoma cells overexpressing full-length exon 2− (4R0N) human tau isoform (Figure 2A).