MYO7A and respiratory distress syndrome in premature infants: To find an AAV-based strategy that efficiently transduces large genes in PR, which are a major target of gene therapy for IRDs including STGD and USH1B, we compared the retinal transduction properties of the AAV OZ with those of dual AAV TS and hybrid AK approaches, which in addition to dual AAV OV were the best performing dual AAV approaches in vitro.