MDM2 and neoplasm: Some tumour promoting genes, related to cell growth and survival, like the early growth response 1 (EGR1), the fatty acid synthase (FASN) and the mouse double minute 2 homolog (MDM2), resulted in fact strongly down-regulated (Table 1 and Figure 6a), whereas pro-apoptotic or tumor suppressor genes, as the caspase2 (CASP2), the programmed cell death 10 (PDCD10), the non metastatic cells 1 protein (NME1), and the secreted protein acidic and rich in cysteine (SPARC) were up-regulated (Table 1 and Figure 6b).