In the liver tissue, the mRNA levels of PPARα and its target genes peroxisome proliferator-activated receptor-γ coactivator-1β (PGC-1β) and cytochrome P450, family 4, subfamily a, polypeptide 10 (Cyp4a10) were increased in HF+LP and HF+BB groups relative to the HF control group, whereas the gene expression of Fatty acid synthase (FAS) and Acyl-CoA oxidase (ACO) were markedly inhibited. The gene discussed is PPARA; the disease is hydrops fetalis.