Other viruses such as bovine herpesvirus-1 (BHV-1) have also been used to express IFN-γ and the stability of the BHV-1/IFN-γ virus as well as its immunomodulating effects studied upon primary infection and following reactivation of a latent infection [53]. The gene discussed is IFNG; the disease is disease arising from reactivation of latent virus.