To determine whether the change in total core fucosylation in GC tumors was related to altered glycosylation biosynthesis, the abundance of mammalian α-1,6-fucosyltransferase (Fut8) and guanosine diphosphate transporter (GDP-Tr) in GC tumors and adjacent tissue was analyzed by RT-PCR. The gene discussed is FUT8; the disease is gastric cancer.