Lysophosphatidic acid (LPA) is a known chemotactic molecule for cells [30] and wild-type Lysophosphatidic acid receptor 1 (LPAR1) has been shown to increase cell motility, invasion and metastasis in breast, liver, lung and colon cancers [25,62-66]. The gene discussed is LPAR1; the disease is malignant colon neoplasm.