Following validation by real-time quantitative RT-PCR and flow cytometry, we selected two representative differentially-expressed BMDM and microglia surface markers (SELL and F11R) to demonstrate that infiltrating BMDM in induced murine malignant glioma acquire F11R expression, which was verified using allogeneic bone marrow transplantation. The gene discussed is SELL; the disease is malignant glioma.