ITGAM and central nervous system cancer: Whereas control naïve mice do not form gliomas nor contain significant numbers of CD11b+ CD45high BMDM cells (R3; <2% cells) (Figure S3, Figure 3B), murine gliomas exhibit increased numbers of lymphocytes (R1; 27% cells) as well as CD11b+ CD45low cells (R2, microglia; 39% cells) and CD11b+ CD45high cells (R3, macrophages; 34% cells).