When injected 30 min prior to HAdV-D37 infection, PP2 reduced corneal inflammation as assessed by histology 4 days post infection (Figure 5D) and also reduced CXCL1 expression by ELISA at 16 hr post infection (p<.05, Figure 5E), while the PP2 solvent DMSO alone did not reduce inflammation or CXCL1 expression. This evidence concerns the gene CXCL1 and infection.