The study aims, to develop a metric that stratifies recommended dietary iron intake to compensate for non-menstrual hemorrhagic losses, and evaluate whether iron deficiency can be attributed to under-replacement of hemorrhagic iron losses in HHT, were achieved: Here we present the hemorrhage-adjusted iron requirement (HAIR), that, together with hepcidin/ferritin relationships and hematinic validations, establish HHT as a model of hemorrhagic iron deficiency. Here, HAMP is linked to nutritional disorder.