Post infection with LCMV WE, fgl2−/− mice had increased numbers of CD138+CD19lowCD45Rlow plasma cells, as well as increased titers of both total LCMV specific and LCMV neutralizing antibody whereas fgl2+/+ mice failed to mount an effective B cells response even long after viral clearance as has previously been reported [36]. This evidence concerns the gene FGL2 and infection.