The first article by Karmiloff-Smith et al. (2012) presents two case-studies of children with partial genetic deletions in the WS critical region (WSCR)—which encompasses about 28 genes deleted from one copy of chromosome 7: a girl with 24 of 28 genes deleted in the WSCR, and a boy with the opposite profile, i.e., only 4 genes deleted at the telomeric end of the WSCR (including GTF2I, which has been implicated in elevated levels of sociability typical of WS, in prior research). This evidence concerns the gene GTF2I and Werner syndrome.