CMYA5 and Duchenne muscular dystrophy: Furthermore, absence or malfunction of myospryn is observed in a couple of muscle diseases including tibial and limb-girdle muscular dystrophies (TMD and LGMD2J, respectively) (Sarparanta et al., 2010) as well as the most abundant and severe form of muscular dystrophies, i.e., DMD (Reynolds et al., 2008).