SNORA23 and glaucoma: When this glaucoma/control ratio by fibril diameter bin was evaluated in each mouse strain, the steepest slope (greater increase in small and decrease in large fibrils) was seen in Aca23 mutants (r2=0.82, p<0.0001, Figure 6D), followed by CD1 (r2=0.36, p=0.0001, Figure 6B), with no significant slopes for B6 (r2=0.01, p=0.8, Figure 6A) or Aca23-WT (r2=0.08, p=0.12, Figure 6C).