MEIS1 and leukemia: More recent findings also support the oncogenetic role of miR-196b in MLL-rearranged leukemia suggesting that miR-196b could contribute to the unfavorable prognosis of MLL-rearranged leukemia by repressing simultaneously the expression of both oncogenic (HOXA9/MEIS1) and tumour-suppressor (FAS) target genes [113].