The miR-26 family is transcriptionally repressed by the c-Myc oncogene, which is highly up-regulated in many different types of hematological malignancies, including Burkitt lymphoma, B-cell lymphoma, and diffuse large-B-cell lymphoma and different types of leukemia [51,52]. The gene discussed is MYC; the disease is B-cell non-Hodgkin lymphoma.