For the susceptibility loci of 14q13.3, as 14q was reported to be specifically linked with MNG1 and a form of MNG with PTC [25,26], it is worth to mention that the risk T allele of rs944289 was presented in the sequences of the most family members affected with thyroid disease (II2 & II8, MNG; II5 & III2, MNG with PTC; Table 1). This evidence concerns the gene DICER1 and toxic multinodular goitre.