ALPP and cancer: Yohsinaru et al. reported that the expression of glycosylphosphatidylinositol-anchored carcinoembryonic Ag (CEA) and ALP on the cell surface of a variety of cancer cell lines and a lung diploid cell line (WI38) upon exposure of the cell lines to a cell differentiation agent (sodium butyrate) to induce cell differentiation and expression of the two tumor-associated Ags [38].