Compared with the mild hepatitis group, the moderate hepatitis group had increased AST and 5′NT and decreased 5-mC levels; the severe hepatitis group had elevated ALT and AST and reduced RBP levels; the liver failure group had higher PT and INR levels and lower PT%, Tp, Alb, CHE, and RBP levels (all P<0.05). The gene discussed is ALB; the disease is Hepatic failure.