Among the 61 SNPs, eight SNPs (rs4415084 of 5p12/MRPS30, rs6557161 of 6q25/ESR1, rs7465364 of 8p21/RPL17p33, rs672888 of 8q24/MYC, rs10509168 of 10q21/ZNF365, rs1219648 of 10q26/FGFR2, rs17221259 of 12p13/ATF7IP and rs3803662 of 16q12/TOX3) showed suggestive association (P-value<0.05) with breast cancer in Japanese population (Table 3). Here, ESR1 is linked to breast cancer.