Recent evidence shows that CCR2+ monocyte recruitment also plays an important role in photoreceptor degeneration in models of retinitis pigmentosa (Guo et al, 2012), photo-oxidative stress (Rutar et al, 2012; Suzuki et al, 2012), and in the carboxyethylpyrrole-immunization induced model of AMD (Cruz-Guilloty et al, 2013). Here, CCR2 is linked to age-related macular degeneration.