CCL2 levels were significantly increased in AMD patients with GA (Fig 1A), while CX3CL1 levels were around 10 times lower and comparable in both groups (controls: 0.08 ng/ml ±0.004 SEM; GA: 0.085 ng/ml ±0.003 SEM). This evidence concerns the gene CX3CL1 and age-related macular degeneration.