Given the previously described promoting role of decorin on endothelial cells and on angiogenesis in cornea (Fiedler & Eble, 2009; Nelimarkka et al, 2001; Schonherr et al, 1999; Schonherr et al, 2001; Schonherr et al, 2004), we tested whether decorin produced by MB49-I cells would favour angiogenesis within the tumour bed. This evidence concerns the gene DCN and neoplasm.