Notably, when analysing isolated tumour cell lines, we observed that only a small proportion of them (2/34) actually express decorin (Fig 7A), suggesting that the tumour microenvironment promotes decorin expression by the tumour cells in situ, or, alternatively, that part of the expression of decorin in patients biopsies could come from activated myofibroblasts surrounding the tumour cells. Here, DCN is linked to neoplasm.