At the termination of the experiment, tumor volume in the four groups reached 853.401 ± 187.3, 782.39 ± 153.1, 771.904 ± 139.2, 373.078 ± 82.1 mm3 for PBS, Lipo, or NC, CTSB-shRNA, respectively (P > 0.05). Here, CTSB is linked to neoplasm.