Although gene scans have shown that the expression of luteinizing hormone/choriogonadotropin receptor (LH/CGR) in breast cancer is either undetectable or very low (11), studies have identified that LHCGR may be detected in breast cancer cells (12–14) and that LH participates in the tumor progression of breast cancer using LHCGR. The gene discussed is PLOD1; the disease is neoplasm.