In cisplatin-resistant Caov-3 ovarian cancer cells, the inhibition of NF-κB activity by treatment with specific NF-κB nuclear translocation inhibitors (SN-50) or by the transfection of p50 ΔNLS, which lacks the nuclear localization signal domain, increased the efficacy of cisplatin-induced apoptosis (44). Here, NFKB1 is linked to ovarian carcinoma.