The insertion in exon 20 of the HER2 gene (insertion version A775YVMA or M774AYVM) was indicated in a single patient, who only had material from the NSCLC metastatic lesion available (0.67% of all analyzed patients and 1.5% of adenocarcinoma patients; Fig. 1). Here, ERBB2 is linked to non-small cell lung carcinoma.