Furthermore, LIGHT may induce the expression of Mig and IP-10, chemotactic factors in antitumor angiogenesis, inhibit tumor angiogenesis and act with natural killer (NK) cells (18) and accelerate antitumor T-cell immunity, which may result in delayed growth or the spontaneous regression of tumors (4), all indicating that LIGHT may be an significant antitumor factor. This evidence concerns the gene TNFSF14 and neoplasm.