Moreover, EGFR overexpression due to polymorphisms has been observed in several other types of tumors, including breast and gastrointestinal cancer (29,34–36), and EGFR inhibitors were able to inhibit the metastasis and invasiveness of tumor cells, including lung cancers, even at a low dose that had no significant effect on primary tumor growth (38,39). The gene discussed is EGFR; the disease is lung cancer.