Prostate-specific antigen (PSA) tumor marker levels were >500 ng/ml (reference value, 0–35 ng/ml), however, other tumor markers, including α-fetoprotein (AFP), carcinoembryonic antigen (CEA), carbohydrate antigen (CA)19-9, CA12-5 and neuron-specific enolase (NSE) remained within the normal ranges. This evidence concerns the gene ENO2 and neoplasm.