TIPE2 and renal cell carcinoma: Therefore, in the present study, the TIPE2 mRNA expression levels in cancer tissue samples from RCC patients were compared with controls, and the correlations between TIPE2 mRNA expression levels and the TNM staging of RCC and the mRNA expression levels of myxoma resistance protein (MX1), an interferon (IFN)-I-inducible gene, were analyzed (13).