Previous studies have shown that specific clinical and molecular factors have predictive values for postoperative prognosis: Advanced tumor stages; circulating molecules, including C-reactive protein and erythrocyte polyamines; molecules in the tumor, including L1 cell adhesion molecules; and chromosomal variations, including 10q and 13q deletions, and D9S168 micro-satellite alterations. Here, L1CAM is linked to neoplasm.