HPGDS and renal cell carcinoma: SNPs of metabolic enzymes, including cytochrome P450 mono-oxygenases, N-acetyltransferase and glutathione S-transferase, are associated with RCC risk in Caucasians; although, these correlations have not been replicated in Chinese individuals (4,10), indicating that the association between genetic predisposition and RCC risk alters among various populations.