By contrast, direct injection of miRNAs indicated that the luciferase-positive area was relatively small in NOD/SCID mice, but was increased in uPA-NOG mice at day 28 (Fig. 2B), suggesting that the effects of the SeV vector infection were more apparent than the in vivo transfection of miRNAs, and that the extracellular structure of the liver and immunosurveillance may alter the effect. Here, PLAU is linked to infection.