TGFB1 and steatosis: TGF-β1 expression in the model control group was significantly increased compared with that of the normal control group, and the majority of the expression was observed in the portal area, central vein wall, proliferated fibrous septum, liver sinus wall, small bile duct cells, inflammatory cells and fatty and hepatic cells with steatosis and hydropic degeneration (Fig. 1B).