MMP1 and tuberculosis: However, after 24 h of stimulation with M. tuberculosis, MMP-1, MMP-7, and MMP-10 transcripts were observed to be significantly higher in the PBMC cultures of TB-IRIS as compared with those of non-IRIS patients (pcorr = 0.02, pcorr = 0.05 and p = 0.01, respectively) (Supporting Information Table 3).