After Bonferroni correction, MMP gene induction was significantly higher in TB-IRIS than in non-IRIS controls for MMP-3, and MMP-10 at 6 h (pcorr ≤ 0.05), while at 24 h, significant differences existed between TB-IRIS and non-IRIS participants for MMP-7 (pcorr ≤ 0.001). Here, MMP7 is linked to tuberculosis.