Although no significant correlation was observed in CDDP-sensitive nodule after each adjustment (data not shown), the HCC growth rate in the CDDP-resistant group was positively correlated with CDDP dose in an exponential fashion after normalization by Ccr (Fig. 3a, P = 0.0017, r = 0.57) or with both albumin and Ccr (Fig. 3b, P = 0.013, r = 0.47). Here, ALB is linked to hepatocellular carcinoma.