VEGFA and neoplasm: Similar findings were reported in a study by Skog et al., where they detect tumour-specific EGFRvIII in serum EVs of glioblastoma patients.24 Moreover, they demonstrated that EVs are enriched in angiogenic proteins (interleukin-6, interleukin-8, VEGF) and that they stimulate tubule formation by endothelial cells.24