SOX10 and malignant peripheral nerve sheath tumor: Karamchandani et al. [18] reported that of 78 MPNST studied 18 were positive for both S100 and SOX10 (23%), 13 (17%) were S100+/SOX10-, 3 (4%) were S100-/SOX10+, and 44 cases (56%) were negative for both (the sensitivity of S100 for detecting MPNST was 40% and the sensitivity of SOX10 was 27%).