However, the overexpression of src in the p53 mutant fish resulted in the development of steatosis, hyperplasia, dysplasia, and HCC; moreover, sarcomatoid HCC characterized by pleomorphic spindle tumor cells growing in haphazard, fascicular patterns was observed in three out of five cases of HCC (Figure 6B2 to B6). The gene discussed is TP53; the disease is neoplasm.