While without stimulation ADAM10 was found at comparably high levels on all cell types analyzed (Figure 1), ADAM17 was almost not detectable on T cells and only present at low levels on some tumor cell types, e.g. pancreatic ductal adenocarcinoma (Panc89) and fibrosarcoma (HT1080) cell lines (Figure 6). Here, ADAM10 is linked to neoplasm.