NFKB1 and necrotizing enterocolitis: Since proinflammatory effects of PAF play prominent roles in the pathogenesis of IBD and NEC, it was of great interest to investigate the effects of probiotic Lactobacilli in counteracting PAF-induced NF-κB activation via CARMA3-Bcl10-MALT1 signalosome and to elucidate the underlying mechanisms.