In control subjects, the SLE-risk (G) allele of rs3122605 was dose-dependently associated with elevated IL10 expression at both mRNA (n = 55; P = 0.001, R2 = 0.18 in linear regression) and protein (n = 116; P = 3.3×10−7, R2 = 0.21) levels (Figure 2). Here, IL10 is linked to systemic lupus erythematosus.